Endocrine Abstracts

A 22 year old lady, in her third pregnancy, presented at 35 weeks gestation with modest hypertension (BP 130/90). She was known to carry a high risk mutation for Von Hippel Lindau syndrome with no prior disease manifestations. Urinary catecholamine levels were normal at 18 weeks gestation and she remained asymptomatic throughout her pregnancy. Repeat measurement at 35 weeks demonstrated elevated noradrenaline and normetadrenaline values (1761 nmol/24h and 9.69 micromol/24h res...

The association between Cushing's syndrome and pregnancy is uncommon due to associated sub-fertility. Recognising this is important, as there implications for both mother and foetus.A twenty year old presented at twenty three weeks gestation. Insulin requiring diabetes had developed as had oedema. Pigmented abdominal striae were prominent. Her serum sodium concentration was noted to be low (3 mmol/l). 24 hour urinary free cortisol was elevated (>1380 ...